Data on File at Align Technology, as of April 26, 2018

https://aaoinfo.org/whats-trending/when-should-my-child-see-an-orthodontist-age-7/

Study sponsored by Align Technology and based on adult Class I, nonextraction, mild to moderate crowding cases with SmartTrack material. David W. White, Katie C. Julien, Helder Jacob, Phillip M. Campbell and Peter H. Buschang, Discomfort associated with Invisalign and traditional brackets: A randomized, prospective trial. The Angle Orthodontist Nov 2017, Vol. 87, No. 6 pp. 801-808

4,5,6 Data on file at Align Technology. As of the end of Q3 2021, and includes all aligner appliances (retainers, templates and aligners).

7,15 Compared to Invisalign aligners previously made from single-layer (EX30) material.

8,14 Compared to Invisalign aligners previously made from single-layer (EX30) material. In a study by Miller et al, with adults measuring pain in the first week of treatment. Kevin Miller et al. “A comparison of treatment impacts between Invisalign aligner and fixed appliance therapy during the first week of treatment.” American Journal of Orthodontics and Dentofacial Orthopedics. Volume 131, Issue 3, pp. 302. e1-302.e9, March 2007.

Based on significantly lower Plaque Index (PI), probing depth (PD), and Bleeding on Probing (BOP) of the upper right first molar and upper left central incisors at initial, 3,6, and 12 months as well as full month plaque score (FMPS) and full mouth bleeding score (FMBS) score at initial and 12 months and better higher compliance with oral hygiene on 50 teenager patients (age 10-18, (25 invisalign treatment, 25 fixed appliances).

10 n a satisfaction rating of 1-9, 1 being ‘not at all satisfied’ and 9 being ‘extremely satisfied’, Invisalign Canadian adult patients (Qty:56) rated satisfaction score of 7.3 vs Canadian metal braces adult patients (Qty: 84) rated satisfaction score of 6.6.

11 https://www.mayoclinic.org/diseases-conditions/cavities/symptoms-causes/syc-20352892

12 Buschang et al; Comparative time efficiency of aligner therapy and conventional edgewise braces. Angle Orthod 1 May 2014; 84 (3): 391–396.
Borda et al; Outcome assessment of orthodontic clear aligner vs fixed appliance treatment in a teenage population with mild malocclusions. Angle Orthod 1 July 2020; 90 (4): 485–490.

13 Data on File at Align Technology, as of July 12 2017: *Based on a global claims survey by Actionable Research of Invisalign providers, respondents were asked the following question: In what percent of cases do patients require an emergency visit? (Global respondents N= 898)

16 https://www.psychologytoday.com/us/blog/humanizing-the-world-work/202111/smiling-why-it-s-important-in-your-personal-life-and-workplace